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Structural Dynamics of Agonist and Antagonist Binding to the Androgen Receptor

Androgen receptor (AR) is a steroid hormone nuclear receptor which upon binding its endogenous androgenic ligands (agonists), testosterone and dihydrotestosterone (DHT), alters gene transcription producing a diverse range of biological effects. Anti-androgens, such as the pharmaceuticals bicalutamid...

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Détails bibliographiques
Publié dans:J Phys Chem B
Auteurs principaux: Singam, Ettayapuram Ramaprasad Azhagiya, Tachachartvanich, Phum, Merrill, Michele A. La, Smith, Martyn T., Durkin, Kathleen A.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742532/
https://ncbi.nlm.nih.gov/pubmed/31431014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b05654
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