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Structural Dynamics of Agonist and Antagonist Binding to the Androgen Receptor
Androgen receptor (AR) is a steroid hormone nuclear receptor which upon binding its endogenous androgenic ligands (agonists), testosterone and dihydrotestosterone (DHT), alters gene transcription producing a diverse range of biological effects. Anti-androgens, such as the pharmaceuticals bicalutamid...
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| Veröffentlicht in: | J Phys Chem B |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6742532/ https://ncbi.nlm.nih.gov/pubmed/31431014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b05654 |
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