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A post-invasion role for Chlamydia type III effector TarP in modulating the dynamics and organization of host cell focal adhesions

The human pathogen Chlamydia trachomatis targets epithelial cells lining the genital mucosa. We observed that infection of various cell types, including fibroblasts and epithelial cells resulted in the formation of unusually stable and mature focal adhesions that resisted disassembly induced by the...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Pedrosa, António T., Murphy, Korinn N., Nogueira, Ana T., Brinkworth, Amanda J., Thwaites, Tristan R., Aaron, Jesse, Chew, Teng-Leong, Carabeo, Rey A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586217/
https://ncbi.nlm.nih.gov/pubmed/32843479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015219
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