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A post-invasion role for Chlamydia type III effector TarP in modulating the dynamics and organization of host cell focal adhesions

The human pathogen Chlamydia trachomatis targets epithelial cells lining the genital mucosa. We observed that infection of various cell types, including fibroblasts and epithelial cells resulted in the formation of unusually stable and mature focal adhesions that resisted disassembly induced by the...

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Foilsithe in:J Biol Chem
Main Authors: Pedrosa, António T., Murphy, Korinn N., Nogueira, Ana T., Brinkworth, Amanda J., Thwaites, Tristan R., Aaron, Jesse, Chew, Teng-Leong, Carabeo, Rey A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586217/
https://ncbi.nlm.nih.gov/pubmed/32843479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015219
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