GDF11 inhibits cardiomyocyte pyroptosis and exerts cardioprotection in acute myocardial infarction mice by upregulation of transcription factor HOXA3

NLRP3 (Nucleotide-binding oligomerization domain-like receptor pyrin domain-containing 3) inflammasome-mediated cardiomyocytes pyroptosis plays a crucial part in progression of acute myocardial infarction (MI). GDF11 (Growth Differentiation Factor 11) has been reported to generate cytoprotective eff...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Li, Zhange, Xu, Honglin, Liu, Xin, Hong, Yang, Lou, Han, Liu, Heng, Bai, Xue, Wang, Lei, Li, Xia, Monayo, Seth Mikaye, Mokembo, Justine Nyakango, Jha, Nabanit Kumar, Yang, Baofeng, Zhang, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585938/
https://ncbi.nlm.nih.gov/pubmed/33100331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03120-6
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