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ISL Induces Apoptosis and Autophagy in Hepatocellular Carcinoma via Downregulation of PI3K/AKT/mTOR Pathway in vivo and in vitro

AIMS: Isoliquiritigenin (ISL), a flavonoid from Glycyrrhiza glabra, has previously been reported to have anti-tumor effects in vivo and in vitro. However, the mechanisms whereby ISL exerts its anticancer effects remain poorly understood in hepatocellular carcinoma (HCC). PURPOSE: In the present stud...

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Dades bibliogràfiques
Publicat a:Drug Des Devel Ther
Autors principals: Song, Lei, Luo, Yi, Li, Shaoling, Hong, Ming, Wang, Qi, Chi, Xiaoling, Yang, Cong
Format: Artigo
Idioma:Inglês
Publicat: Dove 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585813/
https://ncbi.nlm.nih.gov/pubmed/33116421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S270124
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