Design and Rationale for First-in-Human Phase 1 Immunovirotherapy Clinical Trial of Oncolytic HSV G207 to Treat Malignant Pediatric Cerebellar Brain Tumors

Brain tumors represent the most common pediatric solid neoplasms and leading cause of childhood cancer-related morbidity and mortality. Although most adult brain tumors are supratentorial and arise in the cerebrum, the majority of pediatric brain tumors are infratentorial and arise in the posterior...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hum Gene Ther
Prif Awduron: Bernstock, Joshua D., Bag, Asim K., Fiveash, John, Kachurak, Kara, Elsayed, Galal, Chagoya, Gustavo, Gessler, Florian, Valdes, Pablo A., Madan-Swain, Avi, Whitley, Richard, Markert, James M., Gillespie, G. Yancey, Johnston, James M., Friedman, Gregory K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc., publishers 2020
Pynciau:
Protocol—Clinical Development
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585605/
https://ncbi.nlm.nih.gov/pubmed/32657154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2020.101
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