Evaluation the interaction of ABC multidrug transporter MDR1 with thymoquinone: substrate or inhibitor?

OBJECTIVE(S): Thymoquinone (TQ) has valuable medical properties like anticancer effects. Development of multidrug resistance (MDR) phenotype is one of the most important factors in failure of cancer chemotherapy. The aim of this study was to evaluate the mode of interaction of TQ and MDR1, a major M...

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Dades bibliogràfiques
Publicat a:Iran J Basic Med Sci
Autors principals: Keyvani, Vahideh, Nasserifar, Zeinab, Saberi, Mohammad-Reza, Mohajeri, Seyed Ahmad, Arabzadeh, Sepideh, Shahriari Ahmadi, Farajollah, Hosseinzadeh, Hossein, Shariat Razavi, Seyedeh Mahya, Kalalinia, Fatemeh
Format: Artigo
Idioma:Inglês
Publicat: Mashhad University of Medical Sciences 2020
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585528/
https://ncbi.nlm.nih.gov/pubmed/33149871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2020.44216.10381
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