Evaluation the interaction of ABC multidrug transporter MDR1 with thymoquinone: substrate or inhibitor?

OBJECTIVE(S): Thymoquinone (TQ) has valuable medical properties like anticancer effects. Development of multidrug resistance (MDR) phenotype is one of the most important factors in failure of cancer chemotherapy. The aim of this study was to evaluate the mode of interaction of TQ and MDR1, a major M...

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Detalhes bibliográficos
Publicado no:Iran J Basic Med Sci
Main Authors: Keyvani, Vahideh, Nasserifar, Zeinab, Saberi, Mohammad-Reza, Mohajeri, Seyed Ahmad, Arabzadeh, Sepideh, Shahriari Ahmadi, Farajollah, Hosseinzadeh, Hossein, Shariat Razavi, Seyedeh Mahya, Kalalinia, Fatemeh
Formato: Artigo
Idioma:Inglês
Publicado em: Mashhad University of Medical Sciences 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585528/
https://ncbi.nlm.nih.gov/pubmed/33149871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2020.44216.10381
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