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Analysis of Xq27.3 Fragility Using the Micronucleus-Fluorescence In situ Hybridization Assay
Chromosome fragile sites tend to form gap or break in chromosomes when the cells are exposed to replication stress. Folic acid deprivation in the culture medium induces folate-sensitive rare fragile sites, such as FRAXA which is responsible for the fragile X mental retardation syndrome. Chromosome i...
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| Publicado no: | Genome Integr |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wolters Kluwer - Medknow
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7585461/ https://ncbi.nlm.nih.gov/pubmed/33110486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/genint.genint_4_20 |
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