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Analysis of Xq27.3 Fragility Using the Micronucleus-Fluorescence In situ Hybridization Assay

Chromosome fragile sites tend to form gap or break in chromosomes when the cells are exposed to replication stress. Folic acid deprivation in the culture medium induces folate-sensitive rare fragile sites, such as FRAXA which is responsible for the fragile X mental retardation syndrome. Chromosome i...

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Publicado en:Genome Integr
Main Authors: Özer, Leyla, Ruhi, Hatice Ilgın, Bökesoy, Işık
Formato: Artigo
Idioma:Inglês
Publicado: Wolters Kluwer - Medknow 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585461/
https://ncbi.nlm.nih.gov/pubmed/33110486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/genint.genint_4_20
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