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Analysis of Xq27.3 Fragility Using the Micronucleus-Fluorescence In situ Hybridization Assay

Chromosome fragile sites tend to form gap or break in chromosomes when the cells are exposed to replication stress. Folic acid deprivation in the culture medium induces folate-sensitive rare fragile sites, such as FRAXA which is responsible for the fragile X mental retardation syndrome. Chromosome i...

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Bibliografske podrobnosti
izdano v:Genome Integr
Main Authors: Özer, Leyla, Ruhi, Hatice Ilgın, Bökesoy, Işık
Format: Artigo
Jezik:Inglês
Izdano: Wolters Kluwer - Medknow 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585461/
https://ncbi.nlm.nih.gov/pubmed/33110486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/genint.genint_4_20
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