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Neddylation blockade induces HIF-1α driven cancer cell migration via upregulation of ZEB1
Neddylation is a process by which NEDD8 is covalently conjugated to target proteins by sequential enzymatic reaction. Its role in cancer cell migration has only been recently acknowledged. Previously in cancer cell migration, the epithelial to mesenchymal transition (EMT) process has been well-known...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7585416/ https://ncbi.nlm.nih.gov/pubmed/33097763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75286-0 |
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