Ex vivo radiosensitivity is increased in non-cancer patients taking valproate

BACKGROUND: Valproate (VPA) is a commonly prescribed antiepileptic drug for patients experiencing epileptic seizures due to brain tumors. VPA increases radiation sensitivity in various tumor cells in vitro due to complex mechanisms. This could make tumors more vulnerable to ionizing radiation or ove...

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Udgivet i:BMC Neurol
Main Authors: Stritzelberger, Jenny, Lainer, Jennifer, Gollwitzer, Stefanie, Graf, Wolfgang, Jost, Tina, Lang, Johannes D., Mueller, Tamara M., Schwab, Stefan, Fietkau, Rainer, Hamer, Hajo M., Distel, Luitpold
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585294/
https://ncbi.nlm.nih.gov/pubmed/33099323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12883-020-01966-z
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