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Ex vivo radiosensitivity is increased in non-cancer patients taking valproate

BACKGROUND: Valproate (VPA) is a commonly prescribed antiepileptic drug for patients experiencing epileptic seizures due to brain tumors. VPA increases radiation sensitivity in various tumor cells in vitro due to complex mechanisms. This could make tumors more vulnerable to ionizing radiation or ove...

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Detalhes bibliográficos
Publicado no:BMC Neurol
Main Authors: Stritzelberger, Jenny, Lainer, Jennifer, Gollwitzer, Stefanie, Graf, Wolfgang, Jost, Tina, Lang, Johannes D., Mueller, Tamara M., Schwab, Stefan, Fietkau, Rainer, Hamer, Hajo M., Distel, Luitpold
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585294/
https://ncbi.nlm.nih.gov/pubmed/33099323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12883-020-01966-z
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