Caloric restriction alleviates aging-related fibrosis of kidney through downregulation of miR-21 in extracellular vesicles

Glomerulosclerosis and renal interstitial fibrosis occur with the aging kidney. In this study, we examined the expression of miR-21, peroxisome proliferator-activated receptor(PPARα), hypoxia-inducible factor(HIF-1α) in the kidney of 3-month-old rats fed ad libitum (YAL), 24-month-old rats fed ad li...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Liu, Jin-rui, Cai, Guang-yan, Ning, Yi-chun, Wang, Jing-chao, Lv, Yang, Guo, Ya-nan, Fu, Bo, Hong, Quan, Sun, Xue-feng, Chen, Xiang-mei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585074/
https://ncbi.nlm.nih.gov/pubmed/32963130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103591
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