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Glioblastoma cell differentiation trajectory predicts the immunotherapy response and overall survival of patients

Glioblastoma (GBM) is the most common and lethal primary brain tumor. In this study, we aimed to investigate the differentiation states of GBM cells and their clinical relevance. Integrated single-cell RNA-sequencing (scRNA-seq) data and bulk RNA-seq data from GBM samples were used for analysis. Two...

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Detalles Bibliográficos
Publicado en:Aging (Albany NY)
Autores principales: Wang, Zihao, Guo, Xiaopeng, Gao, Lu, Wang, Yu, Ma, Wenbin, Xing, Bing
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585071/
https://ncbi.nlm.nih.gov/pubmed/32957084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103695
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