Glioblastoma cell differentiation trajectory predicts the immunotherapy response and overall survival of patients

Glioblastoma (GBM) is the most common and lethal primary brain tumor. In this study, we aimed to investigate the differentiation states of GBM cells and their clinical relevance. Integrated single-cell RNA-sequencing (scRNA-seq) data and bulk RNA-seq data from GBM samples were used for analysis. Two...

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Vydáno v:Aging (Albany NY)
Hlavní autoři: Wang, Zihao, Guo, Xiaopeng, Gao, Lu, Wang, Yu, Ma, Wenbin, Xing, Bing
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585071/
https://ncbi.nlm.nih.gov/pubmed/32957084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103695
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