The C-Terminal Domain of Clostridioides difficile TcdC Is Exposed on the Bacterial Cell Surface

Clostridioides difficile is an anaerobic Gram-positive bacterium that can produce the large clostridial toxins toxin A and toxin B, encoded within the pathogenicity locus (PaLoc). The PaLoc also encodes the sigma factor TcdR, which positively regulates toxin gene expression, and TcdC, which is a put...

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Veröffentlicht in:J Bacteriol
Hauptverfasser: Oliveira Paiva, Ana M., de Jong, Leen, Friggen, Annemieke H., Smits, Wiep Klaas, Corver, Jeroen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585056/
https://ncbi.nlm.nih.gov/pubmed/32868401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00771-19
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