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Adhesion-GPCR Gpr116 (ADGRF5) expression inhibits renal acid secretion

The diversity and near universal expression of G protein-coupled receptors (GPCR) reflects their involvement in most physiological processes. The GPCR superfamily is the largest in the human genome, and GPCRs are common pharmaceutical targets. Therefore, uncovering the function of understudied GPCRs...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Zaidman, Nathan A., Tomilin, Viktor N., Hassanzadeh Khayyat, Naghmeh, Damarla, Mahendra, Tidmore, Josephine, Capen, Diane E., Brown, Dennis, Pochynyuk, Oleh M., Pluznick, Jennifer L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584995/
https://ncbi.nlm.nih.gov/pubmed/33004624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007620117
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