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Angiotensin II increases activity of the ClC-K2 Cl(−) channel in collecting duct intercalated cells by stimulating production of reactive oxygen species

The renal collecting duct plays a critical role in setting urinary volume and composition, with principal cells transporting Na(+) and K(+) and intercalated cells mediating Cl(−) reabsorption. Published evidence implies Angiotensin II (Ang II) is a potent regulator of the collecting duct apical tran...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Khayyat, Naghmeh Hassanzadeh, Zaika, Oleg, Tomilin, Viktor N., Pyrshev, Kyrylo, Pochynyuk, Oleh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949157/
https://ncbi.nlm.nih.gov/pubmed/33524393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100347
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