FGFR3(△7–9) promotes tumor progression via the phosphorylation and destabilization of ten-eleven translocation-2 in human hepatocellular carcinoma

Overexpression of fibroblast growth factor receptor 3 (FGFR3) correlates with more severe clinical features of hepatocellular carcinoma (HCC). Our previous study has shown that FGFR3(∆7–9), a novel splicing mutation of FGFR3, contributes significantly to HCC malignant character, but the epigenetic m...

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Опубликовано в: :Cell Death Dis
Главные авторы: Jin, Zhijian, Feng, Haoran, Liang, Juyong, Jing, Xiaoqian, Zhao, Qiwu, Zhan, Ling, Shen, Baiyong, Cheng, Xi, Su, Liping, Qiu, Weihua
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584635/
https://ncbi.nlm.nih.gov/pubmed/33097695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03089-2
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