Effects of a single transient transfection of Ten-eleven translocation 1 catalytic domain on hepatocellular carcinoma

Tumor suppressor genes (TSGs), including Ten-eleven translocation 1 (TET1), are hypermethylated in hepatocellular carcinoma (HCC). TET1 catalytic domain (TET1-CD) induces genome-wide DNA demethylation to activate TSGs, but so far, anticancer effects of TET1-CD are unclear. Here we showed that after...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Yuying, Zhu, Hui, Zhang, Zhenxue, Tu, Changchun, Yao, Dongyuan, Wen, Bin, Jiang, Ru, Li, Xing, Yi, Pengfei, Zhan, Jiejie, Hu, Jiaping, Ding, Jianwu, Jiang, Liping, Zhang, Fanglin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294611/
https://ncbi.nlm.nih.gov/pubmed/30551127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207139
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