Native mass spectrometry of human carbonic anhydrase I and its inhibitor complexes

ABSTRACT: Native mass spectrometry is a potent technique to study and characterize biomacromolecules in their native state. Here, we have applied this method to explore the solution chemistry of human carbonic anhydrase I (hCA I) and its interactions with four different inhibitors, namely three sulf...

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Veröffentlicht in:J Biol Inorg Chem
Hauptverfasser: Zoppi, Carlotta, Nocentini, Alessio, Supuran, Claudiu T., Pratesi, Alessandro, Messori, Luigi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2020
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584553/
https://ncbi.nlm.nih.gov/pubmed/32926233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-020-01818-8
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