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The Roles of Mitochondrial Folate Metabolism in Supporting Mitochondrial DNA Synthesis, Oxidative Phosphorylation, and Cellular Function

Folate-mediated one-carbon metabolism (FOCM) is compartmentalized within human cells to the cytosol, nucleus, and mitochondria. The recent identifications of mitochondria-specific, folate-dependent thymidylate [deoxythymidine monophosphate (dTMP)] synthesis together with discoveries indicating the c...

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Dettagli Bibliografici
Pubblicato in:Curr Dev Nutr
Autori principali: Xiu, Yuwen, Field, Martha S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584446/
https://ncbi.nlm.nih.gov/pubmed/33134792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa153
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