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Learning gene networks underlying clinical phenotypes using SNP perturbation

Availability of genome sequence, molecular, and clinical phenotype data for large patient cohorts generated by recent technological advances provides an opportunity to dissect the genetic architecture of complex diseases at system level. However, previous analyses of such data have largely focused o...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Main Authors: McCarter, Calvin, Howrylak, Judie, Kim, Seyoung
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584257/
https://ncbi.nlm.nih.gov/pubmed/33095769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007940
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