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Learning gene networks underlying clinical phenotypes using SNP perturbation

Availability of genome sequence, molecular, and clinical phenotype data for large patient cohorts generated by recent technological advances provides an opportunity to dissect the genetic architecture of complex diseases at system level. However, previous analyses of such data have largely focused o...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: McCarter, Calvin, Howrylak, Judie, Kim, Seyoung
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584257/
https://ncbi.nlm.nih.gov/pubmed/33095769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007940
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