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Heteromerization of Endogenous Mu and Delta Opioid Receptors Induces Ligand-Selective Co-Targeting to Lysosomes

Increasing evidence indicates that native mu and delta opioid receptors can associate to form heteromers in discrete brain neuronal circuits. However, little is known about their signaling and trafficking. Using double-fluorescent knock-in mice, we investigated the impact of neuronal co-expression o...

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Publicado en:Molecules
Autores principales: Derouiche, Lyes, Pierre, Florian, Doridot, Stéphane, Ory, Stéphane, Massotte, Dominique
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583997/
https://ncbi.nlm.nih.gov/pubmed/33007971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25194493
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