Long Noncoding RNA PVT1 Is Regulated by Bromodomain Protein BRD4 in Multiple Myeloma and Is Associated with Disease Progression

Long noncoding RNAs (lncRNAs) are deregulated in human cancers and are associated with disease progression. Plasmacytoma Variant Translocation 1 (PVT1), a lncRNA, is located adjacent to the gene MYC, which has been linked to multiple myeloma (MM). PVT1 is expressed in MM and is associated with carci...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Handa, Hiroshi, Honma, Kazuki, Oda, Tsukasa, Kobayashi, Nobuhiko, Kuroda, Yuko, Kimura-Masuda, Kei, Watanabe, Saki, Ishihara, Rei, Murakami, Yuki, Masuda, Yuta, Tahara, Ken-ichi, Takei, Hisashi, Kasamatsu, Tetsuhiro, Saitoh, Takayuki, Murakami, Hirokazu
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583953/
https://ncbi.nlm.nih.gov/pubmed/32992461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197121
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