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DNA Mismatch Repair in the Chromatin Context: Mechanisms and Therapeutic Potential
DNA mismatch repair (MMR) maintains genomic stability primarily by correcting replication errors. Defects in MMR lead to cancers and cause resistance to many chemotherapeutic drugs. Emerging evidence reveals that MMR is coupled with replication and precisely regulated in the context of chromatin; st...
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| Publicado en: | DNA Repair (Amst) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7583346/ https://ncbi.nlm.nih.gov/pubmed/33087261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2020.102918 |
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