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DNA Mismatch Repair in the Chromatin Context: Mechanisms and Therapeutic Potential
DNA mismatch repair (MMR) maintains genomic stability primarily by correcting replication errors. Defects in MMR lead to cancers and cause resistance to many chemotherapeutic drugs. Emerging evidence reveals that MMR is coupled with replication and precisely regulated in the context of chromatin; st...
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| 發表在: | DNA Repair (Amst) |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7583346/ https://ncbi.nlm.nih.gov/pubmed/33087261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2020.102918 |
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