Amyloid-β peptides slightly affect lifespan or antimicrobial peptide gene expression in Drosophila melanogaster

BACKGROUND: Beta-amyloid peptide (Aβ) is the key protein in the pathogenesis of Alzheimer’s disease, the most common age-related neurodegenerative disorder in humans. Aβ peptide induced pathological phenotypes in different model organisms include neurodegeneration and lifespan decrease. However, rec...

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Dettagli Bibliografici
Pubblicato in:BMC Genet
Autori principali: Shaposhnikov, Mikhail V., Zemskaya, Nadezhda V., Koval, Lyubov А., Minnikhanova, Natalya R., Kechko, Olga I., Mitkevich, Vladimir A., Makarov, Alexander A., Moskalev, Alexey А.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583308/
https://ncbi.nlm.nih.gov/pubmed/33092519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-020-00866-y
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