Yes-associated protein (YAP) induces a secretome phenotype and transcriptionally regulates plasminogen activator Inhibitor-1 (PAI-1) expression in hepatocarcinogenesis

BACKGROUND: Overexpression and nuclear enrichment of the oncogene yes-associated protein (YAP) cause tumor initiation and support tumor progression in human hepatocellular carcinoma (HCC) via cell autonomous mechanisms. However, how YAP expression in tumor cells affects intercellular communication w...

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Bibliografiske detaljer
Udgivet i:Cell Commun Signal
Main Authors: Marquard, Simone, Thomann, Stefan, Weiler, Sofia M. E., Bissinger, Michaela, Lutz, Teresa, Sticht, Carsten, Tóth, Marcell, de la Torre, Carolina, Gretz, Norbert, Straub, Beate K., Marquardt, Jens, Schirmacher, Peter, Breuhahn, Kai
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583285/
https://ncbi.nlm.nih.gov/pubmed/33097058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00634-6
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