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Modulation of the Apurinic/Apyrimidinic Endonuclease Activity of Human APE1 and of Its Natural Polymorphic Variants by Base Excision Repair Proteins

Human apurinic/apyrimidinic endonuclease 1 (APE1) is known to be a critical player of the base excision repair (BER) pathway. In general, BER involves consecutive actions of DNA glycosylases, AP endonucleases, DNA polymerases, and DNA ligases. It is known that these proteins interact with APE1 eithe...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kladova, Olga A., Alekseeva, Irina V., Saparbaev, Murat, Fedorova, Olga S., Kuznetsov, Nikita A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583023/
https://ncbi.nlm.nih.gov/pubmed/32998246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197147
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