Substrate specificity of human apurinic/apyrimidinic endonuclease APE1 in the nucleotide incision repair pathway

Human apurinic/apyrimidinic (AP) endonuclease APE1 catalyses the hydrolysis of phosphodiester bonds on the 5′ side of an AP-site (in the base excision repair pathway) and of some damaged nucleotides (in the nucleotide incision repair pathway). The range of substrate specificity includes structurally...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Kuznetsova, Alexandra A, Matveeva, Anna G, Milov, Alexander D, Vorobjev, Yuri N, Dzuba, Sergei A, Fedorova, Olga S, Kuznetsov, Nikita A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265485/
https://ncbi.nlm.nih.gov/pubmed/30329131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky912
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