Identifying genetic factors that contribute to the increased risk of congenital heart defects in infants with Down syndrome

Atrioventricular septal defects (AVSD) are a severe congenital heart defect present in individuals with Down syndrome (DS) at a > 2000-fold increased prevalence compared to the general population. This study aimed to identify risk-associated genes and pathways and to examine a potential polygenic...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Trevino, Cristina E., Holleman, Aaron M., Corbitt, Holly, Maslen, Cheryl L., Rosser, Tracie C., Cutler, David J., Johnston, H. Richard, Rambo-Martin, Benjamin L., Oberoi, Jai, Dooley, Kenneth J., Capone, George T., Reeves, Roger H., Cordell, Heather J., Keavney, Bernard D., Agopian, A.J., Goldmuntz, Elizabeth, Gruber, Peter J., O’Brien, James E., Bittel, Douglas C., Wadhwa, Lalita, Cua, Clifford L., Moskowitz, Ivan P., Mulle, Jennifer G., Epstein, Michael P., Sherman, Stephanie L., Zwick, Michael E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582922/
https://ncbi.nlm.nih.gov/pubmed/33093519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74650-4
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky