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A short peptide of the C-terminal class Y helices of apolipoprotein A-I has preserved functions in cholesterol efflux and in vivo metabolic control

Apolipoprotein A-I (ApoA-I) of high-density lipoprotein (HDL) induces glucose uptake by muscle tissues and stimulates pancreatic insulin secretion, and also facilitates cholesterol transport in circulation, and is explored for anti-diabetic and anti-atherosclerotic treatments. As the better alternat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Edmunds, Shelley J., Liébana-García, Rebeca, Stenkula, Karin G., Lagerstedt, Jens O.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582918/
https://ncbi.nlm.nih.gov/pubmed/33093642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75232-0
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