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Antiproliferative Properties of a Few Auranofin-Related Gold(I) and Silver(I) Complexes in Leukemia Cells and their Interferences with the Ubiquitin Proteasome System

A group of triethylphosphine gold(I) and silver(I) complexes, structurally related to auranofin, were prepared and investigated as potential anticancer drug candidates. The antiproliferative properties of these metal compounds were assessed against two leukemia cell lines, i.e., CCRF-CEM and its mul...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Cirri, Damiano, Schirmeister, Tanja, Seo, Ean-Jeong, Efferth, Thomas, Massai, Lara, Messori, Luigi, Micale, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582876/
https://ncbi.nlm.nih.gov/pubmed/32998355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25194454
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