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Magnolol Enhances the Therapeutic Effects of TRAIL through DR5 Upregulation and Downregulation of c-FLIP and Mcl-1 Proteins in Cancer Cells

Magnolol is a biologically active compound, isolated from the Chinese herb Magnolia, that regulates antiproliferative, anticancer, antiangiogenic and antimetastatic activities. We found that magnolol sensitizes TRAIL-induced apoptotic cell death via upregulation of DR5 and downregulation of cellular...

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Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Woo, Seon Min, Min, Kyoung-jin, Kwon, Taeg Kyu
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582760/
https://ncbi.nlm.nih.gov/pubmed/33050112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25194591
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