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What Role Does COA6 Play in Cytochrome C Oxidase Biogenesis: A Metallochaperone or Thiol Oxidoreductase, or Both?

Complex IV (cytochrome c oxidase; COX) is the terminal complex of the mitochondrial electron transport chain. Copper is essential for COX assembly, activity, and stability, and is incorporated into the dinuclear Cu(A) and mononuclear Cu(B) sites. Multiple assembly factors play roles in the biogenesi...

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Foilsithe in:Int J Mol Sci
Main Authors: Maghool, Shadi, Ryan, Michael T., Maher, Megan J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582641/
https://ncbi.nlm.nih.gov/pubmed/32977416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21196983
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