Drug Development and the Use of Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Disease Modeling and Drug Toxicity Screening

Over the years, numerous groups have employed human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) as a superb human-compatible model for investigating the function and dysfunction of cardiomyocytes, drug screening and toxicity, disease modeling and for the development of novel drug...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ovics, Paz, Regev, Danielle, Baskin, Polina, Davidor, Mor, Shemer, Yuval, Neeman, Shunit, Ben-Haim, Yael, Binah, Ofer
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582587/
https://ncbi.nlm.nih.gov/pubmed/33023024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197320
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