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The Roles of SPOP in DNA Damage Response and DNA Replication

Speckle-type BTB/POZ protein (SPOP) is a substrate recognition receptor of the cullin-3 (CUL3)/RING type ubiquitin E3 complex. To date, approximately 30 proteins have been identified as ubiquitinated substrates of the CUL3/SPOP complex. Pathologically, missense mutations in the substrate-binding dom...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Maekawa, Masashi, Higashiyama, Shigeki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582541/
https://ncbi.nlm.nih.gov/pubmed/33023230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197293
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