Ceramide-Enriched Membrane Domains Contribute to Targeted and Nontargeted Effects of Radiation through Modulation of PI3K/AKT Signaling in HNSCC Cells

We investigated the potential involvement of ceramide-enriched membrane domains in radiation-induced targeted and nontargeted effects using head and neck squamous cell carcinoma with opposite radiosensitivities. In radiosensitive SCC61 cells, the proportion of targeted effects was 34% and nontargete...

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Udgivet i:Int J Mol Sci
Main Authors: Ladjohounlou, Riad, Louati, Safa, Lauret, Alexandra, Gauthier, Arnaud, Ardail, Dominique, Magne, Nicolas, Alphonse, Gersende, Rodriguez-Lafrasse, Claire
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582380/
https://ncbi.nlm.nih.gov/pubmed/33003449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197200
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