p53-independent early and late apoptosis is mediated by ceramide after exposure of tumor cells to photon or carbon ion irradiation

BACKGROUND: To determine whether ceramide is responsible for the induction of p53-independent early or late apoptosis in response to high- and low-Linear-Energy-Transfer (LET) irradiation. METHODS: Four cell lines displaying different radiosensitivities and p53-protein status were irradiated with ph...

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Detalhes bibliográficos
Main Authors: Alphonse, Gersende, Maalouf, Mira, Battiston-Montagne, Priscillia, Ardail, Dominique, Beuve, Michaël, Rousson, Robert, Taucher-Scholz, Gisela, Fournier, Claudia, Rodriguez-Lafrasse, Claire
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621616/
https://ncbi.nlm.nih.gov/pubmed/23530619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-151
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