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Histone Deacetylase Inhibition in Non-small Cell Lung Cancer: Hype or Hope?
Epigenetic modulation, including acetylation, methylation, phosphorylation, and ubiquitination, plays a pivotal role in regulation of gene expression. Histone acetylation—a balance between the activities of histone acetyltransferases (HATs) and histone deacetylases (HDACs)—is one of the key epigenet...
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| Publicado no: | Front Cell Dev Biol |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7581936/ https://ncbi.nlm.nih.gov/pubmed/33163495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.582370 |
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