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Histone Deacetylase Inhibition in Non-small Cell Lung Cancer: Hype or Hope?

Epigenetic modulation, including acetylation, methylation, phosphorylation, and ubiquitination, plays a pivotal role in regulation of gene expression. Histone acetylation—a balance between the activities of histone acetyltransferases (HATs) and histone deacetylases (HDACs)—is one of the key epigenet...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Mamdani, Hirva, Jalal, Shadia I.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581936/
https://ncbi.nlm.nih.gov/pubmed/33163495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.582370
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