Loss of the Extracellular Matrix Molecule Tenascin-C Leads to Absence of Reactive Gliosis and Promotes Anti-inflammatory Cytokine Expression in an Autoimmune Glaucoma Mouse Model

Previous studies demonstrated that retinal damage correlates with a massive remodeling of extracellular matrix (ECM) molecules and reactive gliosis. However, the functional significance of the ECM in retinal neurodegeneration is still unknown. In the present study, we used an intraocular pressure (I...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wiemann, Susanne, Reinhard, Jacqueline, Reinehr, Sabrina, Cibir, Zülal, Joachim, Stephanie C., Faissner, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581917/
https://ncbi.nlm.nih.gov/pubmed/33162981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.566279
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