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Adenosine and ATPγS protect against bacterial pneumonia-induced acute lung injury

Lipopolysaccharide (LPS), a component of the outer membrane of gram-negative bacteria, disrupts the alveolar-capillary barrier, triggering pulmonary vascular leak thus inducing acute lung injury (ALI). Extracellular purines, adenosine and ATP, protected against ALI induced by purified LPS. In this s...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gross, Christine M., Kovacs-Kasa, Anita, Meadows, Mary Louise, Cherian-Shaw, Mary, Fulton, David J., Verin, Alexander D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581771/
https://ncbi.nlm.nih.gov/pubmed/33093565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75224-0
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