A UHPLC-MS/MS Method for The Quantification of JIB-04 In Rat Plasma: Development, Validation and Application to Pharmacokinetics Study

Methylation of lysine by histone methyltransferases can be reversed by lysine demethylases (KDMs). Different KDMs have distinct oncogenic functions based on their cellular localization, stimulating cancer cell proliferation, reducing the expression of tumor suppressors, and/or promoting the developm...

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Bibliographic Details
Published in:J Pharm Biomed Anal
Main Authors: Wang, Yang, Ma, Jing, Martinez, Elisabeth D., Liang, Dong, Xie, Huan
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581536/
https://ncbi.nlm.nih.gov/pubmed/32892084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2020.113587
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