A UHPLC-MS/MS Method for The Quantification of JIB-04 In Rat Plasma: Development, Validation and Application to Pharmacokinetics Study

Methylation of lysine by histone methyltransferases can be reversed by lysine demethylases (KDMs). Different KDMs have distinct oncogenic functions based on their cellular localization, stimulating cancer cell proliferation, reducing the expression of tumor suppressors, and/or promoting the developm...

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Detalhes bibliográficos
Publicado no:J Pharm Biomed Anal
Main Authors: Wang, Yang, Ma, Jing, Martinez, Elisabeth D., Liang, Dong, Xie, Huan
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581536/
https://ncbi.nlm.nih.gov/pubmed/32892084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2020.113587
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