Human bone marrow stem/stromal cell osteogenesis is regulated via mechanically activated osteocyte‐derived extracellular vesicles

Bone formation or regeneration requires the recruitment, proliferation, and osteogenic differentiation of stem/stromal progenitor cells. A potent stimulus driving this process is mechanical loading. Osteocytes are mechanosensitive cells that play fundamental roles in coordinating loading‐induced bon...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Eichholz, Kian F., Woods, Ian, Riffault, Mathieu, Johnson, Gillian P., Corrigan, Michele, Lowry, Michelle C., Shen, Nian, Labour, Marie‐Noelle, Wynne, Kieran, O'Driscoll, Lorraine, Hoey, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Tissue‐specific Progenitor and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581449/
https://ncbi.nlm.nih.gov/pubmed/32672416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.19-0405
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