DNA Methylation Age Is More Closely Associated With Infection Risk Than Chronological Age in Kidney Transplant Recipients

Older kidney transplant recipients demonstrate increased rates of infection but decreased rates of rejection compared with younger recipients, suggesting that older transplant patients are functionally overimmunosuppressed. We hypothesized that this is a consequence of reduction in immunological act...

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Detalhes bibliográficos
Publicado no:Transplant Direct
Main Authors: Schaenman, Joanna, Zhou, Xinkai, Guo, Rong, Rossetti, Maura, Liang, Emily C., Lum, Erik, Abdalla, Basmah, Bunnapradist, Suphamai, Pham, Phuong-Thu T., Danovitch, Gabriel, Karlamangla, Arun, Reed, Elaine, Horvath, Steve, Elashoff, David
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2020
Assuntos:
Kidney Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581059/
https://ncbi.nlm.nih.gov/pubmed/33134500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000001020
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