DNA Methylation Age Is More Closely Associated With Infection Risk Than Chronological Age in Kidney Transplant Recipients

Older kidney transplant recipients demonstrate increased rates of infection but decreased rates of rejection compared with younger recipients, suggesting that older transplant patients are functionally overimmunosuppressed. We hypothesized that this is a consequence of reduction in immunological act...

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Bibliographic Details
Published in:Transplant Direct
Main Authors: Schaenman, Joanna, Zhou, Xinkai, Guo, Rong, Rossetti, Maura, Liang, Emily C., Lum, Erik, Abdalla, Basmah, Bunnapradist, Suphamai, Pham, Phuong-Thu T., Danovitch, Gabriel, Karlamangla, Arun, Reed, Elaine, Horvath, Steve, Elashoff, David
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2020
Subjects:
Kidney Transplantation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581059/
https://ncbi.nlm.nih.gov/pubmed/33134500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000001020
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