DNA Methylation Age Is More Closely Associated With Infection Risk Than Chronological Age in Kidney Transplant Recipients

Older kidney transplant recipients demonstrate increased rates of infection but decreased rates of rejection compared with younger recipients, suggesting that older transplant patients are functionally overimmunosuppressed. We hypothesized that this is a consequence of reduction in immunological act...

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Bibliografski detalji
Izdano u:Transplant Direct
Glavni autori: Schaenman, Joanna, Zhou, Xinkai, Guo, Rong, Rossetti, Maura, Liang, Emily C., Lum, Erik, Abdalla, Basmah, Bunnapradist, Suphamai, Pham, Phuong-Thu T., Danovitch, Gabriel, Karlamangla, Arun, Reed, Elaine, Horvath, Steve, Elashoff, David
Format: Artigo
Jezik:Inglês
Izdano: Lippincott Williams & Wilkins 2020
Teme:
Kidney Transplantation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581059/
https://ncbi.nlm.nih.gov/pubmed/33134500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000001020
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