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Synthesis and in vivo evaluation of a radiofluorinated ketone body derivative

The ketone bodies d-beta-hydroxybutyric acid and acetoacetic acid represent the principal oxidative energy sources of most tissues when dietary glucose is scarce. An (18)F-labeled ketone body could be a useful tool for studying ketone body metabolism using positron emission tomography (PET). Here, w...

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Pubblicato in:RSC Med Chem
Autori principali: Mattingly, Stephanie J., Wuest, Melinda, Fine, Eugene J., Schirrmacher, Ralf, Wuest, Frank
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7580772/
https://ncbi.nlm.nih.gov/pubmed/33479637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00486f
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