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Biosynthetic Polymalic Acid as a Delivery Nanoplatform for Translational Cancer Medicine
Poly(β-L-malic acid) (PMLA) is a natural polyester produced by numerous microorganisms. Regarding its biosynthetic machinery, a nonribosomal peptide synthetase (NRPS) is proposed to direct polymerization of L-malic acid in vivo. Chemically versatile and biologically compatible, PMLA can be used as a...
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| Опубликовано в: : | Trends Biochem Sci |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier Ltd.
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7580597/ https://ncbi.nlm.nih.gov/pubmed/33268216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2020.09.008 |
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